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工作 经 历
2015/10-presentPrinciple Investigator, College of Life Sciences, South China Agricultural University
2014/01-2015/09Assistant Scientist, Department of Genetics, University of Wisconsin, Madison, USA
2009/01-2013/12Research Associate, Department of Genetics, University of Wisconsin, Madison, USA
教育经历
2001/09-2008/02，美国纽约城市大学研究生院和大学中心（CUNY-Graduate School and University Center），哲学博士，生物化学专业
1998/09-2001/07，中山大学生命科学学院，理学硕士，遗传学专业
1994/09-1998/07，中山大学生命科学学院，理学学士，微生物学专业
研究领域
1. 以拟南芥为模式植物，通过多组学的方法鉴定植物特有的细胞自噬调控因子；
2. 细胞自噬在玉米胚乳发育过程中的作用及调控机制的研究；
3. GWAS挖掘玉米氮素循环利用的主效基因。
科研项目
1. 国家自然科学基金面上项目，拟南芥ABA受体通过选择性细胞自噬降解的分子机制研究，2020/01-2023/12，在研，主持。
2. 国家自然科学基金面上项目，细胞自噬在玉米胚乳发育过程中的作用及调控机制的研究，2018/01-2021/12，在研，主持。
3. 广东省自然科学基金项目，拟南芥抗真菌毒素脱氧雪腐镰刀菌烯醇相关基因的鉴定与功能分析，2021/01-2023/12，在研，主持。
4.中山大学有害生物控制与资源利用国家重点实验室开放课题，2021/01-2023/12，在研，主持。
5. 广东省自然科学基金项目，ATG8互作蛋白FYVE2a/b调控植物细胞自噬的分子机制研究，2018/05-2021/04，在研，参加。
6. 华南农业大学丁颖人才重点培养对象项目，2016始，在研，主持。
7. 华南农业大学******科研启动项目，2015/10始，在研，主持。
发表论文
1.Huang, X., Zheng, C., Liu, F., Yang, C., Zheng, P., Lu, X., Tian, J., Chung, T., Otegui, M.S., Xiao, S., Gao, C., Vierstra, R.D.*, and Li, F.Plant Cell. 31(12): 2973-2995, DOI: https://doi.org/10.1105/tpc.19.00066 (*Co-corresponding author)
2.Xiao Z, Yang C, Liu C, Yang L, Yang S, Zhou J, Li F, Jiang L, Xiao S, Gao C*, Shen W. J.* (2020). SINAT E3 ligases regulate the stability of the ESCRT component FREE1 in response to iron deficiency in plants. Integr Plant Biol. 62:1399-1417.
3.Yang C, Luo M, Zhuang X, Li F, Gao C.* (2020). Transcriptional and epigenetic regulation of autophagy in plants. Trends Genet. 36:676-688.
4.McLoughlin F, Marshall RS, Ding X, Chatt EC, Kirkpatrick LD, Augustine RC, Li FPlant Cell. 32:2699-2724.
5.Yang C, Shen W, Yang L, Sun Y, Li X, Lai M, Wei J, Wang C, Xu Y, Li FMol Plant. 13:515-531.
6.Gou, W., Li, X., Guo, S., Liu, Y., Li, F., and Xie, Q.* (2019). Autophagy in plant: a new orchestrator in the regulation of the phytohormones homeostasis. Int. J. Mol. Sci. 20(12), 2900.
7.Liu, F., Marshall, R.S., and Li, F.* (2018). Understanding and exploiting the roles of autophagy in plants through multi-omics approaches. Plant Sci. 274, 146-152.
8.McLoughlin, F., Augustine, R.C., Marshall, R.S., Li, F., Kirkpatrick, L.D., Otegui, M.S., and Vierstra, R.D.* (2018). Maize multi-omics reveal roles for autophagic recycling in proteome remodelling and lipid turnover. Nat. Plants 4, 1056-1070.
9.Qi, H., Xia, F.N., Xie, L.J., Yu, L.J., Chen, Q.F., Zhuang, X.H., Wang, Q., Li, F., Jiang, L., Xie, Q., and Xiao, S.* (2017). TRAF-family proteins regulate autophagy dynamics by modulating AUTOPHAGY PROTEIN6 stability in Arabidopsis. Plant Cell. 29:890-911.
10.Chen, L., Li, F.*, and Xiao, S.* (2017). Analysis of plant autophagy. Methods Mol Biol 1662, 267-280. (*Co-corresponding author)
11.黄晓, 李发强*. (2016). 细胞自噬在植物细胞程序性死亡中的作用. 植物学报 51, 859-862.
12.Klionsky, D.J.*, and multiple authors including Li F., (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12, 1-222.
13. Li, F., Chung, T., Pennington, J.G., Federico, M.L., Kaeppler, H.F., Kaeppler, S.M., Otegui, M.S., and Vierstra, R.D.* (2015). Autophagic recycling plays a central role in maize nitrogen remobilization. Plant Cell 27, 1389-1408.
14.Marshall, R.S., Li, F., Gemperline, D.C., Book, A.J., and Vierstra, R.D.* (2015). Autophagic degradation of the 26S proteasome is mediated by the dual ATG8/Ubiquitin receptor RPN10 in Arabidopsis. Mol. Cell 58, 1053-1066.
15.Spitzer, C., Li, F., Buono, R., Roschzttardtz, H., Chung, T., Zhang, M., Osteryoung, K.W., Vierstra, R.D., and Otegui, M.S.* (2015). The endosomal protein CHARGED MULTIVESICULAR BODY PROTEIN1 regulates the autophagic turnover of plastids in Arabidopsis. Plant Cell. 27:391-402
16. Li, F., Chung, T., and Vierstra, R.D.* (2014). AUTOPHAGY-RELATED11 plays a critical role in general autophagy- and senescence-induced mitophagy in Arabidopsis. Plant Cell 26, 788-807.
17. Li, F., and Vierstra, R.D.* (2014). Arabidopsis ATG11, a scaffold that links the ATG1-ATG13 kinase complex to general autophagy and selective mitophagy. Autophagy 10, 1466-1467.
18.Klionsky, D.J.*, and multiple authors including Li F., (2012). Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 8, 445-544.
19. Li, F., and Vierstra, R.D.* (2012a). Autophagy: a multifaceted intracellular system for bulk and selective recycling. Trends Plant Sci. 17, 526-537.
20. Li, F., and Vierstra, R.D.* (2012b). Regulator and substrate: dual roles for the ATG1-ATG13 kinase complex during autophagic recycling in Arabidopsis. Autophagy 8, 982-984.
21.Suttangkakul, A., Li, F.#, Chung, T., and Vierstra, R.D.* (2011). The ATG1/ATG13 protein kinase complex is both a regulator and a target of autophagic recycling in Arabidopsis. Plant Cell 23, 3761-3779. (#Co-first author)
22.Chen, Y., Li, F. #, and Wurtzel, E.T.* (2010). Isolation and characterization of the Z-ISO gene encoding a missing component of carotenoid biosynthesis in plants. Plant Physiol. 153, 66-79. (#Co-first author)
23. Li, F., Tsfadia, O., and Wurtzel, E.T.* (2009). The phytoene synthase gene family in the Grasses: subfunctionalization provides tissue-specific control of carotenogenesis. Plant Signal Behav. 4, 208-211.
24. Li, F., Vallabhaneni, R., Yu, J., Rocheford, T., and Wurtzel, E.T.* (2008b). The maize phytoene synthase gene family: overlapping roles for carotenogenesis in endosperm, photomorphogenesis, and thermal stress tolerance. Plant Physiol. 147, 1334-1346.
25. Li, F., Vallabhaneni, R., and Wurtzel, E.T.* (2008a). PSY3, a new member of the phytoene synthase gene family conserved in the Poaceae and regulator of abiotic stress-induced root carotenogenesis. Plant Physiol. 146, 1333-1345.
26. Li, F., Murillo, C., and Wurtzel, E.T.* (2007). Maize Y9 encodes a product essential for 15-cis-zeta-carotene isomerization. Plant Physiol. 144, 1181-1189.
27.Gallagher, C.E., Matthews, P.D., Li, F., and Wurtzel, E.T.* (2004). Gene duplication in the carotenoid biosynthetic pathway preceded evolution of the grasses. Plant Physiol. 135, 1776-1783.
教学活动
承担《分子生物学（双语）》、《细胞生物学（双语）》等本科课程及硕士生《蛋白质翻译后修饰》的教学工作。
指导本科生获2019年第四届全国大学生生命科学创新创业大赛一等奖。
